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Structure Of Kras-G12C Bound To 1-[(4Ar,10P,13R)-10-[5-Amino-4-Fluoro-3-Methyl-2-(Trifluoromethyl)Phenyl]-11-Chloro-9-Fluoro-1,2,4A,5-Tetrahydropyrazino[1',2':4,5][1,4]Oxazino[2,3-C]Quinolin-3(4H)-Yl]Prop-2-En-1-One (Compound 15)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: MG, GDP, A1CII, PEG, GOL, DMS, ACT |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: A1CQ2, GDP, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2026-03-11 Classification: ONCOPROTEIN Ligands: GDP, MG, DMS, EDO, A1AWR, PEG |
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Organism: Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION Resolution:2.49 Å Release Date: 2025-10-22 Classification: TRANSFERASE Ligands: PLG, PEG |
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Organism: Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION Resolution:2.69 Å Release Date: 2025-10-22 Classification: TRANSFERASE Ligands: PLP, SCA, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2025-08-27 Classification: IMMUNE SYSTEM Ligands: A1BLD |
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Inward-Facing, Atp-Bound Multidrug Resistance-Associated Protein 2 (Mrp2) (E1462Q)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-12-18 Classification: TRANSPORT PROTEIN Ligands: ATP, MG, UNL, CLR |
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Outward-Facing, Atp-Bound Multidrug Resistance-Associated Protein 2 (Mrp2) (E1462Q)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-12-18 Classification: TRANSPORT PROTEIN Ligands: ATP, MG, UNL, CLR |
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Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-12-18 Classification: TRANSPORT PROTEIN Ligands: LTX, CLR, UNL |
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Inward-Facing, Ligand-Free Multidrug Resistance-Associated Protein 2 (Mrp2)
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-12-18 Classification: TRANSPORT PROTEIN Ligands: UNL, CLR |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2024-03-13 Classification: HYDROLASE Ligands: EDO, ACT, CYS, TLA |
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Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2024-03-13 Classification: HYDROLASE Ligands: NAG, PO4 |
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Crystal Structure Of Mouse Pld3 Co-Crystallized With 5'Pi-Ssdna For 30 Days
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2024-03-13 Classification: HYDROLASE Ligands: CIT, GOL, ACE, PO4, NAG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2024-03-13 Classification: HYDROLASE/DNA |
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Structure Of An Orthogonal Pyr1*:Hab1* Chemical-Induced Dimerization Module In Complex With Mandipropamid
Organism: Arabidopsis thaliana
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-11-08 Classification: PLANT PROTEIN Ligands: GOL, 3UZ |
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YR2 |
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: SO4, YT2 |
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-10-11 Classification: HYDROLASE Ligands: ZH5 |
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Identification Of Gdc-1971 (Rly-1971), A Shp2 Inhibitor Designed For The Treatment Of Solid Tumors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2023-10-11 Classification: HYDROLASE/INHIBITOR Ligands: ZJX |
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Organism: Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2023-03-15 Classification: TRANSFERASE Ligands: PLP, GOL, ACT |