ISDA: 9YMJ

Deposition Date 2025-10-10

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9YMJ

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

RQd20_wk56_28 Fab in complex with V703-0537_L14 SOSIP and 3BNC117 Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Macaca mulatta (Taxon ID: 9544)
Human immunodeficiency virus 1 (Taxon ID: 11676)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:V703-0537_L14 SOSIP
Chain IDs:E (auth: A), J (auth: B), O (auth: C)
Chain Length:654
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1

Protein Blast

Polymer Type:polypeptide(L)
Molecule:3BNC117 Fab heavy chain
Chain IDs:A (auth: D), F, K (auth: J)
Chain Length:226
Number of Molecules:3
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:3BNC117 light chain
Chain IDs:B (auth: E), G, L (auth: K)
Chain Length:206
Number of Molecules:3
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RQd20_wk56_28 Fab heavy chain
Chain IDs:C (auth: H), H (auth: I), M (auth: N)
Chain Length:231
Number of Molecules:3
Biological Source:Macaca mulatta

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RQd20_wk56_28 light chain
Chain IDs:D (auth: L), I (auth: M), N (auth: O)
Chain Length:212
Number of Molecules:3
Biological Source:Macaca mulatta

Ligand Molecules

NAG

Primary Citation

Vaccination elicits HIV broadly neutralizing antibodies in primates

Steichen, J.M, Madden, P.J, Flynn, C.T, Phulera, S, Shil, M, Kalyuzhniy, O, Liguori, A, Kifude, C, Sewall, L.M, Cottrell, C.A, Ma, K.M, Baboo, S, Diedrich, J.K, McKenney, K, deCamp, A.C, Carnathan, D.G, Phung, I, Ramezani-Rad, P, Marina-Zarate, E, Freeman, B, Xie, Z, Lee, J.H, Sincomb, T, Phelps, N, Lu, D, Goodwin, D, Tingle, R, Adachi, Y, Alavi, N, Tran, J, Tran, A.S, Nascimento, A, Sovie, C, Bader, D.L.V, Voic, H, Zhou, X, Pixton, G, Walsh, A, Melo, M.B, Schiffner, T, Batista, F.D, Burton, D.R, Irvine, D.J, Paulson, J.C, Yates, J.R, Ozorowski, G, Ward, A.B, Silvestri, G, Crotty, S, Schief, W.R.Show

Nature ? ? ? (2026)

DOI: 10.1038/s41586-026-10837-5

Primary Citation of related structures

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