ISDA: 9XZM

Deposition Date 2025-08-27

Release Date 2026-01-28

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9XZM

Keywords:

ISOMERASE/DNA

Title:

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (substrate structure)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

10.27 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*CP*TP*GP*AP*CP*GP*
Chain IDs:D (auth: A)
Chain Length:23
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*CP*GP*CP*TP*AP*
Chain IDs:B
Chain Length:17
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:F-box DNA helicase 1
Gene (Uniprot):FBH1
Chain IDs:E (auth: F)
Chain Length:972
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NFZ0 Pfam ID:PF12937, PF00580, PF13361

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (45-MER)
Chain IDs:A (auth: X)
Chain Length:45
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (45-MER)
Chain IDs:C (auth: Y)
Chain Length:45
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules