9XZL image
Deposition Date 2025-08-27
Release Date 2026-01-28
Last Version Date 2026-03-11
Entry Detail
PDB ID:
9XZL
Keywords:
Title:
Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (body structure)
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cullin-1
Gene (Uniprot):CUL1
Chain IDs:A (auth: C)
Chain Length:776
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:F-box DNA helicase 1
Gene (Uniprot):FBH1
Chain IDs:B (auth: F)
Chain Length:972
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:S-phase kinase-associated pro
Gene (Uniprot):SKP1
Chain IDs:C (auth: S)
Chain Length:163
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (45-MER)
Chain IDs:D (auth: X)
Chain Length:45
Number of Molecules:1
Biological Source:synthetic construct
Primary Citation
Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1.
Nat Commun 17 ? ? (2026)
PMID: 41587991 DOI: 10.1038/s41467-026-68752-2
Primary Citation of related structures
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