ISDA: 9XZJ

Deposition Date 2025-08-27

Release Date 2026-01-28

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9XZJ

Keywords:

ISOMERASE/DNA

Title:

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (consensus structure)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.13 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*CP*TP*GP*AP*CP*GP*
Chain IDs:F (auth: A)
Chain Length:23
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*CP*GP*CP*TP*AP*
Chain IDs:G (auth: B)
Chain Length:17
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cullin-1
Gene (Uniprot):CUL1
Chain IDs:A (auth: C)
Chain Length:776
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q13616 Pfam ID:PF00888, PF26557, PF10557

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:F-box DNA helicase 1
Gene (Uniprot):FBH1
Chain IDs:C (auth: F)
Chain Length:972
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NFZ0 Pfam ID:PF12937, PF00580, PF13361

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase R
Gene (Uniprot):RBX1
Chain IDs:B (auth: R)
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62877 Pfam ID:PF12678 EC:2.3.2.27

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:S-phase kinase-associated pro
Gene (Uniprot):SKP1
Chain IDs:D (auth: S)
Chain Length:163
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63208 Pfam ID:PF03931, PF01466

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (45-MER)
Chain IDs:E (auth: X)
Chain Length:45
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (45-MER)
Chain IDs:H (auth: Y)
Chain Length:45
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules