5UQG image
Deposition Date 2017-02-08
Release Date 2017-03-01
Last Version Date 2026-03-25
Entry Detail
PDB ID:
5UQG
Title:
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p200
Biological Source:
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.03 Å
R-Value Free:
0.20
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
P 1 21 1
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Inosine-5'-monophosphate dehy
Mutagens:the CBS domain (residues 92-195) is replaced with glycine.
Chain IDs:A, B, C, D, E, F, G, H
Chain Length:406
Number of Molecules:8
Biological Source:Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni CG8486
Primary Citation
Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding.
Acs Infect Dis. 11 442 452 (2025)
PMID: 39879323 DOI: 10.1021/acsinfecdis.4c00636
Primary Citation of related structures
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