ISDA: 5UQF

Deposition Date 2017-02-08

Release Date 2017-03-01

Last Version Date 2026-03-25

Entry Detail

PDB ID:

5UQF

Keywords:

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

Title:

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with IMP and the inhibitor P225

Biological Source:

Source Organism(s):

Campylobacter jejuni subsp. jejuni (Taxon ID: 32022)
Campylobacter jejuni subsp. jejuni CG8486 (Taxon ID: 398000)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.73 Å

R-Value Free:

0.22

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

I 4 2 2

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Inosine-5'-monophosphate dehy
Mutagens:the CBS domain (residues 92-195) is replaced with "Gly"
Chain IDs:A, B, C
Chain Length:406
Number of Molecules:3
Biological Source:Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni CG8486

UniProt ID:A0A1B3XFT6,A5KFK9

Ligand Molecules