ISDA: 10SJ

Deposition Date 2026-02-05

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

10SJ

Keywords:

HYDROLASE

Title:

20S Alpha 3 Deletion proteasome core particle in complex with Blm10

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae S288C (Taxon ID: 559292)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE7
Chain IDs:A (auth: 1), O (auth: M)
Chain Length:241
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P23724 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE4
Chain IDs:B (auth: 2), P (auth: N)
Chain Length:266
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P30657 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):SCL1
Chain IDs:C (auth: A), Q (auth: O)
Chain Length:252
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P21243 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE8
Chain IDs:D (auth: B), R (auth: P)
Chain Length:250
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P23639 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE6
Chain IDs:E (auth: C), F (auth: D), S (auth: Q), T (auth: R)
Chain Length:254
Number of Molecules:4
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P40303 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome activator BLM10
Gene (Uniprot):BLM10
Chain IDs:CA, DA
Chain Length:2167
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P43583 Pfam ID:PF16547, PF16507, PF23096, PF11919

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PUP2
Chain IDs:G (auth: E), U (auth: S)
Chain Length:260
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P32379 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE5
Chain IDs:H (auth: F), V (auth: T)
Chain Length:234
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P40302 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PRE10
Chain IDs:I (auth: G), W (auth: U)
Chain Length:288
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P21242 Pfam ID:PF10584, PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE3
Chain IDs:J (auth: H), X (auth: V)
Chain Length:215
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P38624 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP1
Chain IDs:K (auth: I), Y (auth: W)
Chain Length:261
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P25043 Pfam ID:PF00227, PF12465 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PUP3
Chain IDs:L (auth: J), Z (auth: X)
Chain Length:205
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P25451 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE1
Chain IDs:M (auth: K), AA (auth: Y)
Chain Length:198
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P22141 Pfam ID:PF00227 EC:3.4.25.1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PRE2
Chain IDs:N (auth: L), BA (auth: Z)
Chain Length:287
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P30656 Pfam ID:PF00227 EC:3.4.25.1

Ligand Molecules

Primary Citation

Blm10 and PI31 Compromise a Failsafe Mechanism for Proteasome Inhibition

Darlene, F, Rawson, S, Walsh Jr, R.M, Fermin Perez, E, Venclovaite, U, Velez, B, Rajakumar, T, Hanna, J.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form