ISDA: Search

Structural Entry Filters:

Organisms
- Homo sapiens (154)
- Synthetic construct (16)
- Mus musculus (8)
- Staphylococcus aureus (6)
- Ecballium elaterium (4)
- Hepatitis c virus (2)
- Bacillus amyloliquefaciens (2)
- Staphylococcus (1)
- Escherichia coli (1)
Methods
- X-RAY DIFFRACTION (153)
- ELECTRON MICROSCOPY (3)
- SOLUTION NMR (3)
Years
- 2026 (5)
- 2025 (6)
- 2024 (4)
- 2022 (9)
- 2021 (6)
- 2020 (2)
- 2019 (9)
- 2018 (8)
- 2017 (14)
- 2016 (3)
- 2014 (14)
- 2013 (20)
- 2012 (18)
- 2010 (7)
- 2009 (4)
- 2008 (1)
- 2006 (3)
- 2005 (1)
- 2004 (1)
- 2003 (2)
- 2002 (2)
- 2001 (2)
- 2000 (3)
- 1999 (5)
- 1998 (4)
Symmetry
- P 1 21 1 (40)
- P 21 21 21 (28)
- C 1 2 1 (21)
- P 1 (8)
- P 21 21 2 (8)
- C 2 2 21 (6)
- P 62 (6)
- I 2 2 2 (5)
- P 43 21 2 (5)
- P 32 2 1 (5)
- P 31 2 1 (4)
- P 41 (4)
- P 41 21 2 (4)
- P 63 2 2 (2)
- H 3 2 (2)
- P 43 (1)
- P 41 2 2 (1)
- P 31 (1)
- C 2 2 2 (1)
- I 4 (1)
- P 65 2 2 (1)
- P 61 2 2 (1)
- P 42 21 2 (1)
- P 31 1 2 (1)
- P 64 2 2 (1)
Ligands
- EPE (17)
- NAI (10)
- NAD (9)
- LAC (8)
- EOH (6)
- EDO (4)
- ANP (4)
- ADP (2)
- MES (2)
- D3S (2)
- D4S (2)
- NAG (2)
- 9ZS (2)
- 1M3 (2)
- 2OP (2)
- 0X2 (2)
- 0X5 (2)
- JAK (2)
- 0NH (2)
- ATP (2)
- A1CU3 (1)
- A1CWM (1)
- A1CWL (1)
- A1CWK (1)
- 799 (1)
Resolution
- 1.0 - 1.5 (1)
- 1.5 - 2.0 (27)
- 2.0 - 2.5 (66)
- 2.5 - 3.0 (49)
- 3.0 - 3.5 (9)
- 3.5 - 4.0 (1)

Search Count: 159

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9YDM

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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.99 Å Release Date: 2026-01-28
Classification: IMMUNE SYSTEM
Ligands: EOH, GOL, SO4, A1CU3

9YG0

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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.76 Å Release Date: 2026-01-28
Classification: IMMUNE SYSTEM
Ligands: GOL, EOH, MG, A1CWM, SO4

9YG1

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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.97 Å Release Date: 2026-01-28
Classification: IMMUNE SYSTEM
Ligands: EOH, A1CWL, SO4, GOL, MG

9YG2

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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.26 Å Release Date: 2026-01-28
Classification: IMMUNE SYSTEM
Ligands: CL, EDO, GOL, A1CWK, MG

9YG3

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Targeting Ptpn22 At Non-Orthosteric Binding Sites - A Fragment Approach

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.96 Å Release Date: 2026-01-28
Classification: IMMUNE SYSTEM
Ligands: EDO, NA, MG

9DEK

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Usp7 In Complex With Macrocycle Inhibitor Mc02

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: GOL

9DEL

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Usp7 In Complex With Macrocycle Mc03

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.50 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR

9DEM

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Usp7 In Complex With Macrocycle Mc04

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:1.77 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR

9DEN

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Usp7 In Complex With Macrocycle Mc07

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.93 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: EOH

9DEO

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Usp7 In Complex With Macrocycle Inhibitor Mc08

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.70 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: SO4

9DEP

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Usp7 In Complex With Macrocycle Mc09

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.57 Å Release Date: 2025-03-05
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: SO4

8SDM

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Htra-1 Pdsa Bound To Ckp 3B3

Organism: Homo sapiens, Ecballium elaterium
Method: X-RAY DIFFRACTION
Resolution:3.05 Å Release Date: 2024-07-03
Classification: PEPTIDE BINDING PROTEIN

8SDP

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Htra-1 Pdsa Bound To Ckp 3A7

Organism: Homo sapiens, Ecballium elaterium
Method: X-RAY DIFFRACTION
Resolution:2.87 Å Release Date: 2024-07-03
Classification: PEPTIDE BINDING PROTEIN
Ligands: SO4

8SE7

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Htra-1 Pdsa Bound To Ckp 1A8

Organism: Homo sapiens, Ecballium elaterium
Method: X-RAY DIFFRACTION
Resolution:2.96 Å Release Date: 2024-07-03
Classification: PEPTIDE BINDING PROTEIN

8SE8

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Htra-1 Pd/Sa Bound To Ckp 1G10

Organism: Homo sapiens, Ecballium elaterium
Method: X-RAY DIFFRACTION
Resolution:3.18 Å Release Date: 2024-07-03
Classification: PEPTIDE BINDING PROTEIN
Ligands: SO4, GOL

8EXL

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Crystal Structure Of Pi3K-Alpha In Complex With Taselisib

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.99 Å Release Date: 2022-11-30
Classification: CELL CYCLE
Ligands: 799

8EXO

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Crystal Structure Of Pi3K-Alpha In Complex With Compound 19

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.46 Å Release Date: 2022-11-30
Classification: CELL CYCLE
Ligands: X3W

8EXU

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Crystal Structure Of Pi3K-Alpha In Complex With Compound 30

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.68 Å Release Date: 2022-11-30
Classification: CELL CYCLE
Ligands: X3R

8EXV

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Crystal Structure Of Pi3K-Alpha In Complex With Compound 32

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.48 Å Release Date: 2022-11-30
Classification: CELL CYCLE
Ligands: X3N

8ETR

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Cryoem Structure Of Nlrp3 Nacht Domain In Complex With G2394

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2022-11-02
Classification: HYDROLASE
Ligands: MG, ADP, WTN

Protein Functional Filters:

Enzyme
- Transferases (54)
- Hydrolases (39)
- Oxidoreductases (19)
Uniprots
- P00338 (19)
- O60674 (12)
- Q8NBP7 (11)
- P29597 (10)
- Q92743 (9)
- Q93009 (6)
- P48736 (6)
- Q02750 (6)
- P23458 (6)
- Q9Y2R2 (5)
- O14791 (5)
- P01241 (5)
- P42336 (4)
- Q6MZV7 (4)
- O14965 (4)
- P10912 (4)
- A0A0U5BC76 (3)
- P43489 (3)
- A0A097PUG4 (3)
- P01138 (3)
- P01857 (3)
- P08709 (3)
- 184747 (3)
- P0DOX5 (2)
- Q0KKI6 (2)
PFAM
- PF07714 (28)
- PF07654 (20)
- PF00056 (19)
- PF02866 (19)
- PF00613 (10)
- PF00454 (10)
- PF00792 (10)
- PF00794 (10)
- PF00082 (10)
- PF00069 (10)
- PF07686 (9)
- PF13365 (8)
- PF05922 (8)
- PF00443 (6)
- PF00103 (6)
- PF00102 (5)
- PF09067 (5)
- PF02192 (4)
- PF18464 (4)
- PF18459 (4)
- PF18463 (4)
- PF00020 (4)
- PF00041 (4)
- PF00243 (3)
- PF14670 (3)

Structural Entry Filters:

Search Count: 159

Protein Functional Filters:

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