Search Count: 25
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The Discovery Of A Novel Anticoagulant Mechanism: Factor Xi Activation Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.22 Å Release Date: 2026-07-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: A1CJA, NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-07-29
Ligands: A1CJA, NAG
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N-Alkyl &Amp; N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy To Identify Orally Bioavailable Plasma Kallikrein Inhibitors Complex With Compound 15 ((3'R)-1'-(5-Amino-1-Phenyl-1H-Pyrazole-4-Carbonyl)-6-Chloro-5-Fluorospiro[[3,1]Benzoxazine-4,3'-Piperidin]-2(1H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.66 Å Release Date: 2026-04-01 Classification: HYDROLASE/INHIBITOR Ligands: MES, A1C6X, NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-04-01
Ligands: MES, A1C6X, NAG
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N-Alkyl & N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy To Identify Orally Bioavailable Plasma Kallikrein Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2026-03-11 Classification: HYDROLASE/INHIBITOR Ligands: A1C6O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: A1C6O
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N-Alkyl &Amp; N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy To Identify Orally Bioavailable Plasmakallikrein Inhibitors Complex With Compound 4 ((3'R)-1'-(5-Amino-1-Benzyl-1H-Pyrazole-4-Carbonyl)-6-Chloro-5-Fluorospiro[[3,1]Benzoxazine-4,3'-Piperidin]-2(1H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2026-03-11 Classification: HYDROLASE/INHIBITOR Ligands: MES, A1C6Q, NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MES, A1C6Q, NAG
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N-Alkyl &Amp; N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy To Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 25 ((3'R)-1'-{(1P)-5-Amino-1-[2-(Trifluoromethoxy)Phenyl]-1H-Pyrazole-4-Carbonyl}-6-Chloro-5-Fluorospiro[[3,1]Benzoxazine-4,3'-Piperidin]-2(1H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2026-03-11 Classification: HYDROLASE/INHIBITOR Ligands: MES, A1C6Z, NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MES, A1C6Z, NAG
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N-Alkyl &Amp; N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy To Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 13 ((3'R)-1'-{5-Amino-1-[(2S)-1,1,1-Trifluorobutan-2-Yl]-1H-Pyrazole-4-Carbonyl}-6-Chloro-5-Fluorospiro[[3,1]Benzoxazine-4,3'-Piperidin]-2(1H)-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2026-03-11 Classification: HYDROLASE/INHIBITOR Ligands: MES, A1C7M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: MES, A1C7M
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Gsdmd Bound To A Peptide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2025-10-22 Classification: IMMUNE SYSTEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-10-22
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A3R-Gi Complex Bound To Neca
Organism: Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Homo sapiens, Rattus rattus, Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: NEC |
Organism: Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Homo sapiens, Rattus rattus, Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-06
Ligands: NEC
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A3R-Gi Complex Bound To Adenosine
Organism: Rattus rattus, Homo sapiens, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human orthopneumovirus, Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: ADN |
Organism: Rattus rattus, Homo sapiens, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human orthopneumovirus, Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-06
Ligands: ADN
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A3R-Gi Complex Bound To M6A
Organism: Rattus rattus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus, Homo sapiens, Bos taurus, Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: 6MD |
Organism: Rattus rattus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus, Homo sapiens, Bos taurus, Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-06
Ligands: 6MD
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A3R-Gi Complex Bound To I6A
Organism: Rattus rattus, Homo sapiens, Bos taurus, Mus musculus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus
Method: ELECTRON MICROSCOPY Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: ZIR |
Organism: Rattus rattus, Homo sapiens, Bos taurus, Mus musculus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-06
Ligands: ZIR
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A3R-Gi Complex Bound To Namodenoson
Organism: Rattus rattus, Homo sapiens, Bos taurus, Mus musculus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus
Method: ELECTRON MICROSCOPY Release Date: 2024-11-06 Classification: SIGNALING PROTEIN Ligands: XS0 |
Organism: Rattus rattus, Homo sapiens, Bos taurus, Mus musculus, Influenza a virus (a/victoria/3/1975(h3n2)), Ovis aries, Human respiratory syncytial virus
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-06
Ligands: XS0
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Co-Structure Of Pkg1 Regulatory Domain With Compound 33
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2022-08-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: B4I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-24
Ligands: B4I
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Crystal Structure Of Thymidylate Synthase, Thy1, From Thermus Thermophilus Having An Extra C Terminal Domain
Organism: Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2019-06-26 Classification: TRANSFERASE Ligands: FAD, PO4 |
Organism: Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)
Method: X-RAY DIFFRACTION
Release Date: 2019-06-26
Ligands: FAD, PO4
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Crystal Structure Of Human Heteropentameric Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2017-12-06 Classification: PROTEIN BINDING |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-06
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Crystal Structure Of Human Heteroheptameric Complex
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2017-12-06 Classification: PROTEIN BINDING |
Organism: Homo sapiens, Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-12-06
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Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) In Complex With Mk-7655
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2014-02-19 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: MK7 |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2014-02-19
Ligands: MK7
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Crystal Structure Of Maleylacetate Reductase From Rhizobium Sp. Strain Mtp-10005
Organism: Rhizobium
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2014-02-12 Classification: OXIDOREDUCTASE Ligands: SO4, BEN, GOL |
Organism: Rhizobium
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: SO4, BEN, GOL
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Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) In Complex With A Beta-Lactamase Inhibitor
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2011-06-29 Classification: Hydrolase/Hydrolase Inhibitor Ligands: S1Y, CL, IPA |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2011-06-29
Ligands: S1Y, CL, IPA
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Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) In Complex With An Inhibitor
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2011-06-29 Classification: Hydrolase/Hydrolase Inhibitor Ligands: 3S2, CL |
Organism: Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION
Release Date: 2011-06-29
Ligands: 3S2, CL