9PQ1 image
Deposition Date 2025-07-22
Release Date 2026-07-29
Last Version Date 2026-07-29
Entry Detail
PDB ID:
9PQ1
Keywords:
HYDROLASE/HYDROLASE INHIBITOR
Title:
The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation Inhibitors
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Cricetulus griseus
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.22 Å
R-Value Free:
0.29
R-Value Work:
0.25
R-Value Observed:
0.26
Space Group:
P 43 21 2
9PQ1 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Coagulation factor XI
Gene (Uniprot):F11
Chain IDs:A
Chain Length:625
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P03951 Pfam ID:PF00024, PF00089 EC:3.4.21.27
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Kininogen-1 light chain
Gene (Uniprot):KNG1
Chain IDs:B
Chain Length:12
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01042
Ligand Molecules
A1CJA
NAG
Primary Citation
The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation Inhibitors
To Be Published ? ? ? (?)
Primary Citation of related structures
5I25
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