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9S2V image
Nsp14 In Complex With Ligand Tdi-014925-Cl-2 (Compound 58)
Organism: Sars-cov-2 pseudovirus
Method: X-RAY DIFFRACTION
Resolution:2.38 Å Release Date: 2025-09-17
Classification: VIRAL PROTEIN
Ligands: ZN, SAH, A1JLH, CL, IMD

9R5T image
Nsp14 In Complex With Ligand Tdi-016037-Nx-1
Organism: Severe acute respiratory syndrome coronavirus
Method: X-RAY DIFFRACTION
Resolution:1.89 Å Release Date: 2025-08-27
Classification: VIRAL PROTEIN
Ligands: ZN, SAH, A1JDF, CL, EDO, IMD, IPA, SO4

8R7B image
Sars-Cov-2 Nsp14 In Complex With Sah And Tdi-015051
Organism: Sars-cov-2 pseudovirus
Method: X-RAY DIFFRACTION
Resolution:2.18 Å Release Date: 2024-10-23
Classification: VIRAL PROTEIN
Ligands: ZN, SAH, EDO, IMD, YDT, CL

8CO7 image
Crystal Structure Of Human Soluble Adenylyl Cyclase (Sac) In Complex With Inhibitor Tdi-09066
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.90 Å Release Date: 2024-01-03
Classification: SIGNALING PROTEIN
Ligands: V9E, DMS, ACT, EDO, PG4, PGE, CL

8CNH image
Crystal Structure Of Human Soluble Adenylyl Cyclase (Sac) In Complex With Inhibitor Tdi-10512
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2023-04-26
Classification: SIGNALING PROTEIN
Ligands: V6U, DMS, EDO, ACT

8COJ image
Crystal Structure Of Human Soluble Adenylyl Cyclase Catalytic Domain In Complex With The Inhibitor Tdi-10228
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2023-04-26
Classification: SIGNALING PROTEIN
Ligands: VE1, DMS, ACT, EDO

8COT image
Complex Of Human Soluble Adenylyl Cyclase 10 Catalytic Core With Inhibitor Tdi-10962
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2023-04-26
Classification: SIGNALING PROTEIN
Ligands: VBB, DMS, EDO, ACT

8B75 image
Crystal Structure Of Human Soluble Adenylyl Cyclase In Complex With The Inhibitor Tdi-011861
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.82 Å Release Date: 2023-03-29
Classification: SIGNALING PROTEIN
Ligands: PJU

7OVD image
Human Soluble Adenylyl Cyclase In Complex With The Inhibitor Tdi10229
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.20 Å Release Date: 2021-10-06
Classification: SIGNALING PROTEIN
Ligands: 1S2, ACT, DMS, EDO

6WNK image
Macrocyclic Peptides Tdi5575 That Selectively Inhibit The Mycobacterium Tuberculosis Proteasome
Organism: Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION
Resolution:2.28 Å Release Date: 2021-04-28
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: U5Y, CIT, DMF

7KMY image
Structure Of Mtb Lpd Bound To 010705
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION
Resolution:2.21 Å Release Date: 2021-01-27
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Ligands: FAD, WPM, GOL

6OCW image
Crystal Structure Of Mycobacterium Tuberculosis Proteasome In Complex With Phenylimidazole-Based Inhibitor A85
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION
Resolution:2.60 Å Release Date: 2019-10-09
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: DMF, M6M, CIT

6OCZ image
Crystal Structure Of Mycobacterium Tuberculosis Proteasome In Complex With Phenylimidazole-Based Inhibitor A86
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION
Resolution:2.65 Å Release Date: 2019-10-09
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: DMF, M6Y, CIT

6ODE image
Crystal Structure Of Mycobacterium Tuberculosis Proteasome In Complex With Phenylimidazole-Based Inhibitor B6
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION
Resolution:2.90 Å Release Date: 2019-10-09
Classification: HYDROLASE/HYDROLASE INHIBITOR
Ligands: M9G

6PLF image
Crystal Structure Of Human Phgdh Complexed With Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2019-07-24
Classification: OXIDOREDUCTASE/INHIBITOR
Ligands: ONV, EDO

6PLG image
Crystal Structure Of Human Phgdh Complexed With Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.93 Å Release Date: 2019-07-24
Classification: OXIDOREDUCTASE/INHIBITOR
Ligands: ONS, MLT

6MJU image
Human Cgas Catalytic Domain Bound With The Inhibitor G108
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.45 Å Release Date: 2019-05-29
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: JUM, ZN

6MJW image
Human Cgas Catalytic Domain Bound With The Inhibitor G150
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.41 Å Release Date: 2019-05-29
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: ZN, JUJ

6MJX image
Human Cgas Catalytic Domain Bound With Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.60 Å Release Date: 2019-05-29
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 1SY, ZN

5W2E image
Hcv Ns5B Rna-Dependent Rna Polymerase In Complex With Non-Nucleoside Inhibitor Mk-8876
Organism: Hepatitis c virus genotype 1b (isolate bk)
Method: X-RAY DIFFRACTION
Resolution:2.80 Å Release Date: 2017-08-16
Classification: TRANSFERASE/INHIBITOR
Ligands: 9VY
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