ISDA: 9QRU

Deposition Date 2025-04-04

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

9QRU

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of the MMM ubiquitin ligase complex with nanobody 270 (Composite map)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Lama glama (Taxon ID: 9844)

Expression System(s):

Homo sapiens, Escherichia coli k-12

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.03 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Modulator of smoothened prote
Gene (Uniprot):MOSMO
Chain IDs:B (auth: A)
Chain Length:211
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NHV5 Pfam ID:PF18800

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform 2 of Multiple epiderm
Chain IDs:C (auth: B)
Chain Length:477
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q7Z7M0

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nanobody 270
Chain IDs:D (auth: C)
Chain Length:129
Number of Molecules:1
Biological Source:Lama glama

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform 4 of E3 ubiquitin-pro
Gene (Uniprot):MGRN1
Mutagens:R317E
Chain IDs:A (auth: D)
Chain Length:539
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O60291 Pfam ID:PF26192, PF13920 EC:2.3.2.27

Ligand Molecules