9Q3Y image
Deposition Date 2025-08-19
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9Q3Y
Keywords:
MEMBRANE PROTEIN
Title:
GluN1b-GluN2B ATD in complex with radiprodil
Biological Source:
Source Organism(s):
Xenopus laevis (Taxon ID: 8355)
Rattus norvegicus (Taxon ID: 10116)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.74 Å
R-Value Free:
0.22
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
C 1 2 1
9Q3Y validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glutamate receptor ionotropic
Gene (Uniprot):grin1
Chain IDs:A
Chain Length:359
Number of Molecules:1
Biological Source:Xenopus laevis
UniProt ID:A0A1L8F5J9 Pfam ID:PF01094
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glutamate receptor ionotropic
Gene (Uniprot):Grin2b
Chain IDs:B, D
Chain Length:363
Number of Molecules:2
Biological Source:Rattus norvegicus
UniProt ID:Q00960 Pfam ID:PF01094
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glutamate receptor ionotropic
Gene (Uniprot):grin1
Chain IDs:C
Chain Length:358
Number of Molecules:1
Biological Source:Xenopus laevis
UniProt ID:A0A1L8F5J9 Pfam ID:PF01094
Ligand Molecules
A1CNW
CL
NA
NAG
Primary Citation
Inhibition of GluN2B-containing N-methyl-D-aspartate receptors by radiprodil.
Brain 149 976 992 (2026)
PMID: 40994429 DOI: 10.1093/brain/awaf355
Primary Citation of related structures
9Q3Y
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