ISDA: 9O02

Deposition Date 2025-04-01

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9O02

Keywords:

HYDROLASE, LYASE/DNA

Title:

Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state

Biological Source:

Source Organism(s):

Archaeoglobus fulgidus (Taxon ID: 2234)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.50 Å

R-Value Free:

0.27

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 1 21 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:8-oxoguanine DNA glycosylase/
Mutagens:K122S
Chain IDs:A
Chain Length:203
Number of Molecules:1
Biological Source:Archaeoglobus fulgidus

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*AP*GP*AP*GP*TP*
Chain IDs:B
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*GP*CP*AP*GP*GP*
Chain IDs:C
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

MOO

Primary Citation

Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state

Huffman, J.L, Syed, A, Tang, H.Y.H, Arvai, A.S, Mol, C.D, Tainer, J.A.Show

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