ISDA: 9NZA

Deposition Date 2025-03-31

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9NZA

Keywords:

HYDROLASE, LYASE/DNA

Title:

Crystal structure of human OGG1 (WT) in a product bound state in the presence of the agonist F01

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.50 Å

R-Value Free:

0.24

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:N-glycosylase/DNA lyase
Gene (Uniprot):OGG1
Chain IDs:A
Chain Length:319
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O15527 Pfam ID:PF07934, PF00730 EC:3.2.2.23

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*AP*CP*CP*TP*GP*CP
Chain IDs:C (auth: B)
Chain Length:7
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*AP*CP*CP*TP*GP*CP
Chain IDs:B (auth: C)
Chain Length:8
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*GP*CP*AP*GP*GP*
Chain IDs:D
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

OXG

Primary Citation

Crystal structure of human OGG1 (WT) in a product bound state in the presence of the agonist F01

Syed, A, Arvai, A.S, Tainer, J.A.Show

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Primary Citation of related structures

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