ISDA: 10MN

Deposition Date 2026-01-27

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

10MN

Keywords:

HYDROLASE, LYASE/DNA

Title:

Crystal structure of human OGG1 (WT) in a product bound state in the presence of the agonist F51

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.10 Å

R-Value Free:

0.25

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 65 2 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:N-glycosylase/DNA lyase
Gene (Uniprot):OGG1
Chain IDs:A
Chain Length:319
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O15527 Pfam ID:PF07934, PF00730 EC:3.2.2.23

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*AP*CP*CP*TP*GP*C)
Chain IDs:C (auth: B)
Chain Length:7
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*AP*GP*AP*GP*TP*
Chain IDs:B (auth: C)
Chain Length:8
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*GP*CP*AP*GP*GP*
Chain IDs:D
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules