ISDA: 35TW

Deposition Date 2026-05-16

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

35TW

Keywords:

RNA BINDING PROTEIN/RNA

Title:

VIPR Ternary Complex with an ssRNA substrate, Closed Conformation

Biological Source:

Source Organism(s):

Suspvirus SUSP1 (Taxon ID: 1985290)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.94 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:SUSP1 viprRNA
Chain IDs:I (auth: A)
Chain Length:94
Number of Molecules:1
Biological Source:Suspvirus SUSP1

Polymer Type:polyribonucleotide
Molecule:Target ssRNA
Chain IDs:H (auth: B)
Chain Length:21
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Vipr Protein
Chain IDs:A (auth: D), B (auth: E), C (auth: F), D (auth: G), E (auth: H), F (auth: I), G (auth: J)
Chain Length:202
Number of Molecules:7
Biological Source:Suspvirus SUSP1

Ligand Molecules

Primary Citation

VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation

Yoon, P.H, Docter, T.A, Zhang, Z.T, Loi, K, Lopez, S.C, Valentin-Alvarado, L.E, Tuck, O, Brohawn, S.G, Doudna, J.A.Show

Science ? ? ? (2026)

DOI: 10.1126/science.aei3472

Primary Citation of related structures

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