ISDA: 23AK

Deposition Date 2026-01-29

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

23AK

Keywords:

NUCLEAR PROTEIN

Title:

Cryo-EM structure of ATRX ATPase domain bound to a nucleosome

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.03 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3
Gene (Uniprot):LOC121398065
Chain IDs:H (auth: A), J (auth: E)
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A310TTQ1

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:A (auth: B), C (auth: F)
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:P62799

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A
Gene (Uniprot):LOC494591
Chain IDs:B (auth: C), D (auth: G)
Chain Length:129
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:Q6AZJ8

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B
Gene (Uniprot):LOC108704303
Chain IDs:I (auth: D), K (auth: H)
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A8J0U496

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (147-MER)
Chain IDs:E (auth: I)
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (147-MER)
Chain IDs:F (auth: J)
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Chromatin remodeler ATRX
Gene (Uniprot):ATRX
Chain IDs:G (auth: K)
Chain Length:817
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P46100 EC:3.6.4.-

Ligand Molecules

Primary Citation

Structural basis for the non-canonical nucleosome remodeling by ATRX

Wang, X, Yan, S, Huang, Y, Ge, K, Wu, Y, Xu, W, Kang, Y, Yao, D, Liu, X, Chen, Y.Show

Mol.Cell ? ? ? (2026)

Primary Citation of related structures

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