22PC image
Deposition Date 2026-01-19
Release Date 2026-10-28
Last Version Date 2026-10-28
Entry Detail
PDB ID:
22PC
Keywords:
NUCLEAR PROTEIN
Title:
Crystal structure of the histone-binding motif of ATRX in complex with H3-H4-ASF1
Biological Source:
Source Organism(s):
Xenopus laevis (Taxon ID: 8355)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.00 Å
R-Value Free:
0.26
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 1 21 1
22PC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H3
Gene (Uniprot):LOC121398065
Chain IDs:A, D (auth: E)
Chain Length:84
Number of Molecules:2
Biological Source:Xenopus laevis
UniProt ID:A0A310TTQ1
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:B, E (auth: F)
Chain Length:88
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P62805
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone chaperone ASF1B
Gene (Uniprot):ASF1B
Chain IDs:C, F (auth: G)
Chain Length:163
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9NVP2
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcriptional regulator ATR
Gene (Uniprot):ATRX
Chain IDs:G (auth: D), H
Chain Length:23
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P46100 EC:3.6.4.12
Ligand Molecules
NA
Primary Citation
Structural basis for the non-canonical nucleosome remodeling by ATRX
Mol.Cell ? ? ? (2026)
Primary Citation of related structures
22OX
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