ISDA: 11UI

Deposition Date 2026-03-13

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

11UI

Keywords:

MEMBRANE PROTEIN

Title:

GluA2 open state + RR2b + Glu (full-length composite map)

Biological Source:

Source Organism(s):

Rattus norvegicus (Taxon ID: 10116)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.88 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Isoform Flip of Glutamate rec
Chain IDs:A, B, C, D
Chain Length:841
Number of Molecules:4
Biological Source:Rattus norvegicus

Ligand Molecules

FWF

GLU

SPD

Primary Citation

Tuning of AMPA receptor activation by inhibitory auxiliary subunits and epilepsy-associated disease mutations

Newton, T.P, Yelshanskaya, M.V, Aktolun, M, Gangwar, S.P, Yen, L.Y, Alekseev, A.A, Sobolevsky, I.A, Kurnikova, M.G, Sobolevsky, A.I.Show

Nat Commun ? ? ? (2026)

DOI: 10.1038/s41467-026-77416-0

Primary Citation of related structures

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