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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To 1-[(2R,3R)-3-{[(7P)-7-(8-Ethynyl-7-Fluoronaphthalen-1-Yl)-8-Fluoro-2-{ [(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D] Pyrimidin-4-Yl](Methyl)Amino}-2-Methylpyrrolidin-1-Yl]-3-(Pyrazin-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2026-03-04 Classification: HYDROLASE Ligands: GDP, A1C5K, CA |
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Crystal Structure Of Crimean-Congo Hemorrhagic Fever Virus Cap-Snatching Endonuclease
Organism: Orthonairovirus haemorrhagiae, Mus musculus
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2025-12-31 Classification: HYDROLASE |
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Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2025-12-31 Classification: HYDROLASE |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease In Complex With Manganese Ions
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease (E668A Mutant)
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease (E682A Mutant)
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease (D719A Mutant)
Organism: Mus musculus, Kasokero virus
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2025-12-31 Classification: HYDROLASE |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease In Complex With 2,4-Dioxo-4-Phenylbutanoic Acid (Dpba)
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN, XI7 |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease In Complex With L-742,001
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN, 0N8 |
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Crystal Structure Of Kasokero Virus Cap- Snatching Endonuclease In Complex With Baloxavir Acid (Bxa)
Organism: Kasokero virus, Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2025-12-31 Classification: HYDROLASE Ligands: MN, E4Z |
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gmppnp And Covalently Bound To An Adduct Of {(2S)-4-[7-(8-Chloronaphthalen-1-Yl)-2-{[(2S)-1-Methylpyrrolidin-2-Yl]Methoxy}-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl]-1-[(2Z)-2-Fluoro-3-(Pyridin-2-Yl)Prop-2-Enoyl]Piperazin-2-Yl}Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GNP, A1B7P, MG |
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Crystal Structure Of Kirsten Rat Sarcoma G12C Complexed With Gdp And Covalently Bound To An Adduct Of (2S)-1-{4-[(7P)-7-(8-Ethynyl-7-Fluoro-3-Hydroxynaphthalen-1-Yl)-8-Fluoro-2-{[(2R,4R,7As)-2-Fluorotetrahydro-1H-Pyrrolizin-7A(5H)-Yl]Methoxy}Pyrido[4,3-D]Pyrimidin-4-Yl]Piperazin-1-Yl}-2-Fluoro-3-(1,3-Thiazol-2-Yl)Propan-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2025-11-05 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: GDP, A1B7Q, MG |
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Crystal Structure Of Farnesoid X-Activated Receptor Complexed With Compound-32 Aka (1S,3S)-N-({4-[5-(2-Fluoropr Opan-2-Yl)-1,2,4-Oxadiazol-3-Yl]Bicyclo[2.2.2]Octan-1-Yl}M Ethyl)-3-Hydroxy-N-[4'-(2-Hydroxypropan-2-Yl)-[1,1'-Biphen Yl]-3-Yl]-3-(Trifluoromethyl)Cyclobutane-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-06-29 Classification: NUCLEAR PROTEIN Ligands: IUS |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-(4-Fluorophenyl)-N-Methyl-6-[(Methylsulfonyl)Amino]-5-(Propan-2-Yloxy)-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 2N5, SO4, GOL, PG4 |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 2-({3-[1-(2-Cyclopropylethyl)-6-Fluoro-4-Hydroxy-2-Oxo-1,2-Dihydroquinolin-3-Yl]-1,1-Dioxo-1,4-Dihydro-1Lambda~6~,2,4-Benzothiadiazin-7-Yl}Oxy)Acetamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XV, SO4 |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 3-[2-(4-Fluorophenyl)-3-(Methylcarbamoyl)-1-Benzofuran-5-Yl]Benzoic Acid
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.54 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, SO4, 8XS, GOL |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-2-(4-Fluorophenyl)-N-Methyl-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XP, SO4, GOL |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase C316N In Complex With 2-(4-Fluorophenyl)-N-Methyl-5-[3-({2-Methyl-1-Oxo-1-[(1,3,4-Thiadiazol-2-Yl)Amino]Propan-2-Yl}Carbamoyl)Phenyl]-1-Benzofuran-3-Carboxamide
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XM, SO4, GOL |
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Crystal Structure Of The Hepatitis C Virus Ns5B Rna-Dependent Rna Polymerase In Complex With 4-Fluoro-2-(4-Fluorophenyl)-N-Methyl-5-(2-Methyl-5-{[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamoyl}Phenyl)-1-Benzofuran-3-Carboxamide (Bms-929075)
Organism: Hepatitis c virus genotype 1b (isolate con1)
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2017-05-10 Classification: TRANSFERASE Ligands: 23E, 8XJ, SO4, GOL |
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Crystal Structure Of The Hepatitis C Virus Genotype 2A Strain Jfh1 L30S Ns5B Rna-Dependent Rna Polymerase In Complex With 5-[3-(Tert-Butylcarbamoyl)Phenyl]-6-(Ethylamino)-2-(4-Fluorophenyl)-N-Methylfuro[2,3-B]Pyridine-3-Carboxamide
Organism: Hepatitis c virus genotype 2a (isolate jfh-1)
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2017-03-15 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 7NG, SO4, PE5, PG4 |