ISDA: Search

Structural Entry Filters:

Organisms
- Homo sapiens (7,040)
- Mus musculus (1,122)
- Rattus norvegicus (569)
- Synthetic construct (386)
- Escherichia coli (381)
- Bos taurus (324)
- Arabidopsis thaliana (250)
- Saccharomyces cerevisiae (164)
- Drosophila melanogaster (157)
- Lama glama (156)
- Gallus gallus (99)
- Caenorhabditis elegans (86)
- Staphylococcus aureus (81)
- Enterobacteria phage t4 (73)
- Danio rerio (66)
- Halorhodospira halophila (64)
- Pseudomonas aeruginosa (63)
- Thermotoga maritima (61)
- Severe acute respiratory syndrome coronavirus 2 (60)
- Sus scrofa (56)
- Dictyostelium discoideum (49)
- Xenopus laevis (48)
- Mycobacterium tuberculosis (45)
- Escherichia coli (strain k12) (44)
- Oryctolagus cuniculus (42)
Methods
- X-RAY DIFFRACTION (8,669)
- Alphafold (1,888)
- ELECTRON MICROSCOPY (1,767)
- SOLUTION NMR (927)
- SOLID-STATE NMR (11)
- NEUTRON DIFFRACTION (5)
- ELECTRON CRYSTALLOGRAPHY (3)
- SOLUTION SCATTERING (1)
- POWDER DIFFRACTION (1)
Years
- 2026 (211)
- 2025 (717)
- 2024 (712)
- 2023 (681)
- 2022 (637)
- 2021 (612)
- 2020 (624)
- 2019 (650)
- 2018 (511)
- 2017 (502)
- 2016 (504)
- 2015 (411)
- 2014 (440)
- 2013 (425)
- 2012 (380)
- 2011 (377)
- 2010 (353)
- 2009 (365)
- 2008 (433)
- 2007 (339)
- 2006 (342)
- 2005 (217)
- 2004 (233)
- 2003 (114)
- 2002 (98)
Symmetry
- P 1 (2,109)
- P 21 21 21 (1,988)
- P 1 21 1 (1,325)
- C 1 2 1 (854)
- C 2 2 21 (559)
- P 21 21 2 (347)
- P 32 2 1 (310)
- P 41 21 2 (259)
- P 43 21 2 (234)
- P 31 2 1 (215)
- P 65 2 2 (166)
- P 61 2 2 (151)
- H 3 2 (139)
- I 2 2 2 (138)
- H 3 (120)
- P 65 (119)
- P 63 (114)
- P 61 (106)
- I 4 2 2 (96)
- P 41 (95)
- P 43 (73)
- P 2 21 21 (66)
- P 31 (50)
- P 32 (49)
- P 21 3 (49)
Ligands
- NAG (726)
- EDO (689)
- GDP (414)
- PO4 (262)
- GNP (257)
- ACT (225)
- CLR (198)
- PEG (193)
- GTP (172)
- ATP (152)
- ADP (151)
- DMS (150)
- ANP (128)
- HEM (101)
- FMN (94)
- MPD (92)
- PLM (89)
- G1I (80)
- PGE (79)
- IHP (77)
- FMT (75)
- OLC (74)
- MES (63)
- RET (60)
- OLA (59)
Resolution
- <1 (28)
- 1.0 - 1.5 (822)
- 1.5 - 2.0 (2,590)
- 2.0 - 2.5 (2,560)
- 2.5 - 3.0 (1,790)
- 3.0 - 3.5 (747)
- 3.5 - 4.0 (237)
- 4.0 - 4.5 (59)
- 4.5 - 5.0 (23)
- >5 (64)

Search Count: 13,268

Sort:

All Selected

22XC

View CIF | Download

Structure Of Cxcr4 In Complex With A De-Novo Designed Mini-Protein Antagonist

Organism: Synthetic construct, Homo sapiens
Method: ELECTRON MICROSCOPY
Resolution:3.28 Å Release Date: 2026-04-22
Classification: SIGNALING PROTEIN
Ligands: CLR, D21

9OXA

View CIF | Download

Cryoem Structure Of Gi-Coupled Tas2R43 With Aristolochic Acid I

Organism: Homo sapiens, Mus musculus
Method: ELECTRON MICROSCOPY
Resolution:2.90 Å Release Date: 2026-04-22
Classification: SIGNALING PROTEIN
Ligands: GOQ

9OXB

View CIF | Download

Cryoem Structure Of Ggust-Coupled Tas2R43 With Aristolochic Acid I

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Resolution:3.00 Å Release Date: 2026-04-22
Classification: SIGNALING PROTEIN
Ligands: GOQ

9PU1

View CIF | Download

Hras Complex With Um0140401 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:1.40 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PU3

View CIF | Download

Hras Complex With Um0140692 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PU8

View CIF | Download

Hras Complex With Um0140693 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:1.40 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PUL

View CIF | Download

Hras Complex With Um0143525 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.50 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: MG, GDP

9PUN

View CIF | Download

Hras Complex With Um0148697 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PUQ

View CIF | Download

Hras Complex With Um0152248 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PUT

View CIF | Download

Hras Complex With Um0152535 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9PUZ

View CIF | Download

Hras Complex With Um0153030 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: MG, GDP, PO4

9PVE

View CIF | Download

Hras Complex With Um0152533 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP

9PVF

View CIF | Download

Kras Complex With Um0152533 Compound

Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2026-04-22
Classification: HYDROLASE/INHIBITOR
Ligands: GDP, MG

9SZQ

View CIF | Download

Crystal Structure Of The E336K Mutant Of Human Apoptosis Inducing Factor

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2026-04-22
Classification: OXIDOREDUCTASE
Ligands: FAD, GOL

9T7J

View CIF | Download

Cryo-Em Structure Of Akt Phosphorylated Mtor Complex 2, Overall Refinement

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2026-04-22
Classification: TRANSFERASE
Ligands: IHP, ATP, ZN, ADP

9T92

View CIF | Download

Cryo-Em Structure Of Autophosphorylated Mtor Complex 2, Overall Refinement

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2026-04-22
Classification: TRANSFERASE
Ligands: IHP, ZN

9T93

View CIF | Download

Cryo-Em Structure Of Autophosphorylated Mtor Complex 2, Focused On A Single Protomer

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2026-04-22
Classification: TRANSFERASE
Ligands: IHP, ZN

9T94

View CIF | Download

Cryo-Em Structure Of Akt Phosphorylated Mtor Complex 2, Focused On A Single Protomer

Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2026-04-22
Classification: TRANSFERASE
Ligands: IHP, ATP, ADP, ZN

9TBM

View CIF | Download

From Krasg12D To Pan-Kras Inhibitors

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.60 Å Release Date: 2026-04-22
Classification: SIGNALING PROTEIN
Ligands: MG, GDP, A1JU5

9TBR

View CIF | Download

From Krasg12D To Pan-Kras Inhibitors

Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.65 Å Release Date: 2026-04-22
Classification: SIGNALING PROTEIN
Ligands: GDP, MG, A1JU6

Protein Functional Filters:

Enzyme
- Transferases (2,845)
- Hydrolases (2,535)
- Oxidoreductases (172)
- Lyases (99)
- Isomerases (93)
- Ligases (31)
- Translocases (25)
Uniprots
- P62873 (457)
- P59768 (447)
- P63096 (189)
- P01112 (175)
- P28482 (158)
- P63092 (157)
- P01116 (153)
- P0ABE7 (143)
- P07550 (100)
- P31947 (100)
- Q8WWQ0 (88)
- Q9BYC8 (79)
- O75394 (79)
- Q9BQ48 (79)
- Q9NZE8 (79)
- Q9BZE1 (79)
- Q96DV4 (79)
- Q9NYK5 (79)
- Q9NQ50 (79)
- Q8IXM3 (79)
- Q5T653 (79)
- P09001 (79)
- Q9BYD3 (79)
- Q9BYD2 (79)
- Q9Y3B7 (79)
PFAM
- PF00069 (783)
- PF00001 (735)
- PF00071 (612)
- PF00503 (580)
- PF00631 (558)
- PF00400 (492)
- PF07714 (348)
- PF00017 (298)
- PF00240 (277)
- PF00072 (254)
- PF00018 (200)
- PF00244 (200)
- PF25391 (196)
- PF00595 (195)
- PF00439 (192)
- PF01094 (161)
- PF00041 (129)
- PF00454 (127)
- PF00467 (109)
- PF00169 (109)
- PF00276 (108)
- PF00573 (106)
- PF00237 (104)
- PF00238 (103)
- PF00828 (103)

Structural Entry Filters:

Search Count: 13,268

Protein Functional Filters:

Feedback Form