Search Count: 20
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Identification Of Ampd2 Allosteric Inhibitors With Novel Mechanism Of Action By Fragment Merging Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2026-06-17 Classification: METAL BINDING PROTEIN Ligands: ZN, PO4, ES9, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-06-17
Ligands: ZN, PO4, ES9, SO4
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A Potent And Selective Ror Gamma Inhibitor For The Treatment Of Autoimmune Diseases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2026-04-29 Classification: DNA BINDING PROTEIN Ligands: A1MCM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-04-29
Ligands: A1MCM
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Crystal Structure Of Human Inpp5K With An Allosteric Inhibitor Reveals The Structural Basis For Species Specific Potency
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2026-03-11 Classification: TRANSFERASE Ligands: EDO, MLI, A1MDP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-11
Ligands: EDO, MLI, A1MDP
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Hiv-1 Integrase Core Domain In Complex With Potent Allosteric Inhibitors
Organism: Human immunodeficiency virus type 1 (new york-5 isolate)
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2025-12-31 Classification: VIRAL PROTEIN Ligands: A1MCX, 1PE, SO4 |
Organism: Human immunodeficiency virus type 1 (new york-5 isolate)
Method: X-RAY DIFFRACTION
Release Date: 2025-12-31
Ligands: A1MCX, 1PE, SO4
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Crystal Structure Of The Mutant Ror Gamma Lbd With Compound 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2025-07-30 Classification: NUCLEAR PROTEIN Ligands: A1MAM, EDO, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-30
Ligands: A1MAM, EDO, ACT
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Crystal Structure Of The Mutant Human Ror Gamma Ligand Binding Domain With Jte-151
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2024-11-27 Classification: NUCLEAR PROTEIN/INHIBITOR Ligands: YAL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-27
Ligands: YAL
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Optimization Efforts For Identification Of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction Ihhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.32 Å Release Date: 2024-05-22 Classification: PEPTIDE BINDING PROTEIN Ligands: A1LVB, ACT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-05-22
Ligands: A1LVB, ACT, SO4
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Optimization Efforts For Identification Of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction (Ppi) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2024-05-22 Classification: PEPTIDE BINDING PROTEIN Ligands: A1LVC, ACT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-05-22
Ligands: A1LVC, ACT, SO4
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Methyl And Fluorine Effects In Novel Orally Bioavailable Keap1/Nrf2 Ppi Inhibitor For Treatment Of Chronic Kidney Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2023-06-14 Classification: PEPTIDE BINDING PROTEIN Ligands: SGO, DTT, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-14
Ligands: SGO, DTT, SO4
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Methyl And Fluorine Effects In Novel Orally Bioavailable Keap1/Nrf2 Ppi Inhibitor For Treatment Of Chronic Kidney Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2023-06-14 Classification: PEPTIDE BINDING PROTEIN Ligands: SIU, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-14
Ligands: SIU, SO4
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Methyl And Fluorine Effects In Novel Orally Bioavailable Keap1/Nrf2 Ppi Inhibitor For Treatment Of Chronic Kidney Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2023-06-14 Classification: PEPTIDE BINDING PROTEIN Ligands: T6I, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-06-14
Ligands: T6I, SO4
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Discovery Of Functionally Selective Transforming Growth Factor Beta Type Ii Receptor (Tgf-Beta Rii) Inhibitors As Anti-Fibrosis Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2021-06-16 Classification: IMMUNE SYSTEM Ligands: HJF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-06-16
Ligands: HJF
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Discovery Of The Second Generation Ror Gamma Inhibitors Composed Of An Azole Scaffold.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2019-03-06 Classification: NUCLEAR PROTEIN/INHIBITOR Ligands: AYO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-06
Ligands: AYO
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Ternary Complex Of Human Ror Gamma Ligand Binding Domain With Compound T.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2018-12-12 Classification: NUCLEAR PROTEIN/INHIBITOR Ligands: 9P6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-12
Ligands: 9P6
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Crystal Structure Of The Mutant Human Ror Gamma Ligand Binding Domain With Rockogenin.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-06-07 Classification: TRANSFERASE/IHIBITOR Ligands: 82R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 82R
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Crystal Structure Of The Mutant Human Ror Gamma Ligand Binding Domain With Ursolic Acid.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-06-07 Classification: TRANSFERASE/INHIBITOR Ligands: 6Q5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 6Q5
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Crystal Structure Of The Wild Human Ror Gamma Ligand Binding Domain.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2017-06-07 Classification: TRANSFERASE/INHIBITOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
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Crystal Structure Of The Mutant Human Ror Gamma Ligand Binding Domain.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2017-06-07 Classification: TRANSCRIPTION/INHIBITOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
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Crystal Structure Of The Mutant Human Ror Gamma Ligand Binding Domain With Compound A.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2017-06-07 Classification: TRANSFERASE/INHIBITOR Ligands: 82O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-07
Ligands: 82O
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Crystal Structure Of Kshv Protease In Complex With Hexapeptide Phosphonate Inhibitor
Organism: Human herpesvirus
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2007-12-25 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ACT |
Organism: Human herpesvirus
Method: X-RAY DIFFRACTION
Release Date: 2007-12-25
Ligands: ACT