Search Count: 23
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Discovery Of Mta-Cooperative Prmt5 Inhibitors From Co-Factor Directed Dna-Encoded Library Screens
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-05-07 Classification: TRANSFERASE/INHIBITOR Ligands: A1B6Y, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-07
Ligands: A1B6Y, MTA
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From Dna-Encoded Library Screening To Am-9747 - An Mta-Cooperative Prmt5 Inhibitor With Potent Oral In Vivo Efficacy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2025-03-26 Classification: TRANSFERASE/INHIBITOR Ligands: A1BQW, MTA, GOL, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-26
Ligands: A1BQW, MTA, GOL, PEG, DMS
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Amg 193, A Clinical Stage Mta-Cooperative Prmt5 Inhibitor, Drives Anti-Tumor Activity Preclinically And In Patients With Mtap-Deleted Cancers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2024-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, DMS, A1ATH, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: GOL, DMS, A1ATH, MTA
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Solution Structure Of Phage Derived Peptide Inhibitor Of Frizzled 7 Receptor
Organism: Unidentified
Method: SOLUTION NMR Release Date: 2018-04-18 Classification: PROTEIN BINDING |
Organism: Unidentified
Method: SOLUTION NMR
Release Date: 2018-04-18
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Crystal Structure Of Frizzled-7 Crd With An Inhibitor Peptide Fz7-21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.88 Å Release Date: 2018-04-18 Classification: SIGNALING PROTEIN Ligands: HOH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-04-18
Ligands: HOH
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Crystal Structure Of Frizzled 7 Crd In Complex With C24 Fatty Acid
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-10 Classification: IMMUNE SYSTEM Ligands: NER, NAG, SO4, 1PG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: NER, NAG, SO4, 1PG
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Crystal Structure Of Frizzled 5 Crd In Complex With Pam
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-05-10 Classification: SIGNALING PROTEIN Ligands: PAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: PAM
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Crystal Structure Of Frizzled 5 Crd In Complex With Bog
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-05-10 Classification: SIGNALING PROTEIN Ligands: BOG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-10
Ligands: BOG
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Crystal Structure Of Frizzled 7 Crd
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.99 Å Release Date: 2017-04-05 Classification: IMMUNE SYSTEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-04-05
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Human Nav1.7-Vsd4-Navab In Complex With Gx-936.
Organism: Arcobacter butzleri, homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.53 Å Release Date: 2015-12-23 Classification: METAL TRANSPORT Ligands: PX4, 5P2 |
Organism: Arcobacter butzleri, homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-23
Ligands: PX4, 5P2
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Unliganded Crystal Structure Of Mab7
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2013-11-13 Classification: IMMUNE SYSTEM |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2013-11-13
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Inhibitory Mechanism Of An Allosteric Antibody Targeting The Glucagon Receptor
Organism: Mus musculus, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.74 Å Release Date: 2013-11-13 Classification: IMMUNE SYSTEM |
Organism: Mus musculus, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-13
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Structure Of Human Hdac2 In Complex With Saha (Vorinostat)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-08-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, NA, PG4, SHH, NHE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-21
Ligands: ZN, CA, NA, PG4, SHH, NHE
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Structure Of Human Hdac2 In Complex With Inhibitor 4-(Acetylamino)-N-[2-Amino-5-(Thiophen-2-Yl)Phenyl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2013-08-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, NA, PG4, 20Y, NHE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-21
Ligands: ZN, CA, NA, PG4, 20Y, NHE
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A Molecular Basis For Negative Regulation Of The Glucagon Receptor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2012-08-29 Classification: IMMUNE SYSTEM Ligands: NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-29
Ligands: NAG
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Hiv-1 Reverse Transcriptase In Complex With Tmc125
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2010-05-12 Classification: TRANSFERASE Ligands: 65B, SO4 |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2010-05-12
Ligands: 65B, SO4
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Hiv-1 K103N Reverse Transcriptase In Complex With Tmc125
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2010-05-12 Classification: TRANSFERASE Ligands: 65B, SO4, CL |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2010-05-12
Ligands: 65B, SO4, CL
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Hiv-1 Reverse Transcriptase In Complex With Tmc278
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-05-12 Classification: TRANSFERASE Ligands: T27, SO4 |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2010-05-12
Ligands: T27, SO4
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Hiv-1 K103N Reverse Transcriptase In Complex With Tmc278
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2010-05-12 Classification: TRANSFERASE Ligands: T27, SO4 |
Organism: Hiv-1 m:b_hxb2r
Method: X-RAY DIFFRACTION
Release Date: 2010-05-12
Ligands: T27, SO4
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R-State Amp Complex Reveals Initial Steps Of The Quaternary Transition Of Fructose-1,6-Bisphosphatase
Organism: Sus scrofa
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2005-03-22 Classification: HYDROLASE Ligands: F6P, MG, AMP |
Organism: Sus scrofa
Method: X-RAY DIFFRACTION
Release Date: 2005-03-22
Ligands: F6P, MG, AMP