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Egfr Exon20 Insertion Mutant Asv Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, CL, EDO, GOL, PEG |
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Egfr Exon20 Insertion Mutant Svd Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, EDO, GOL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1A4E, CL, EDO, GOL |
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Wildtype Egfr Bound With (R)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN Ligands: A1ILZ |
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Egfr Exon20 Insertion Mutant Npg Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: A1IMS |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2025-05-14 Classification: TRANSFERASE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: CL, A1IMT |
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Organism: Severe acute respiratory syndrome coronavirus 2
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2023-04-05 Classification: VIRAL PROTEIN Ligands: 7ON |
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Organism: Severe acute respiratory syndrome coronavirus 2
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2023-04-05 Classification: VIRAL PROTEIN |
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Crystal Structure Of The Catalytic Domain Of The Inosine Monophosphate Dehydrogenase From Bacillus Anthracis In The Complex With Imp And The Inhibitor P221
Organism: Bacillus anthracis
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2021-06-09 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: IMP, GOL, ZO7, K, EDO |
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Crystal Structure Of The Catalytic Domain Of The Inosine Monophosphate Dehydrogenase From Bacillus Anthracis In The Complex With Imp And The Inhibitor P176
Organism: Bacillus anthracis
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2021-06-09 Classification: OXIDOREDUCTASE Ligands: IMP, ZO4, K |
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Co-Crystal Structure Of Human Nicotinamiden-Methyltransferase (Nnmt) In Complex With High-Affinity Alkynyl Bisubstrate Inhibitor Ns1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2019-10-23 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: N37, GOL |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2017-06-28 Classification: HYDROLASE Ligands: GNP, MG, GOL |
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Crystal Structure Of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed With Imp And P225
Organism: Clostridium perfringens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2017-05-24 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: IMP, 8KY |
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Crystal Structure Of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed With Imp And P221
Organism: Clostridium perfringens (strain atcc 13124 / dsm 756 / jcm 1290 / ncimb 6125 / nctc 8237 / type a)
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-03-22 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: IMP, 8N1, MPD, ACY, FMT, MRD |
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Crystal Structure Of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed With Imp And P182
Organism: Clostridium perfringens (strain atcc 13124 / dsm 756 / jcm 1290 / ncimb 6125 / nctc 8237 / type a)
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2017-03-22 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: IMP, 8L1, K, GOL |
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Crystal Structure Of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed With Imp And P200
Organism: Clostridium perfringens (strain atcc 13124 / dsm 756 / jcm 1290 / ncimb 6125 / nctc 8237 / type a)
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2017-03-22 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: IMP, 8L4, PGE, PEG, EDO, MG, K, PG4 |
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Crystal Structure Of The Catalytic Domain Of The Inosine Monophosphate Dehydrogenase From Bacillus Anthracis In The Complex With Imp And The Inhibitor P178
Organism: Bacillus anthracis
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE Ligands: IMP, 8LA, K, EDO, PO4, GOL, PEG |
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Crystal Structure Of The Catalytic Domain Of The Inosine Monophosphate Dehydrogenase From Bacillus Anthracis In The Complex With Imp And The Inhibitor P200
Organism: Bacillus anthracis
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: IMP, 8L4, K |
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Crystal Structure Of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed With Imp And P178
Organism: Clostridium perfringens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-03-08 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: IMP, 8LA, K, MPD, FMT, SO4 |