Search Count: 23
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Krasg12C In Complex With Asp2453
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2026-03-04 Classification: HYDROLASE Ligands: GDP, MG, A1L9E, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-03-04
Ligands: GDP, MG, A1L9E, SO4
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Crystal Structure Of Cyp46A1 With [(1R,5S)-3-Oxa-8-Azabicyclo[3.2.1]Octan-8-Yl][(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 3K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZE
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Crystal Structure Of Cyp46A1 With (Morpholin-4-Yl)[(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 2H)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZD
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Crystal Structure Of Cyp46A1 With Cyclopropyl[(4M)-4-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)-1H-Indol-1-Yl]Methanone (Compound 2B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZC, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)Phenyl]-N-(Propan-2-Yl)Benzene-1-Sulfonamide (Compound 2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZB, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)-5-(Trifluoromethyl)Phenyl]Benzamide (Compound 3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZA
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Crystal Structure Of Cyp46A1 With N-[6-(1,3-Oxazol-5-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl]Cyclopropanecarboxamide (Compound 4L)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BY9, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BY9, EDO
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Krasg12C In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2024-01-17 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, Y9D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: GDP, MG, Y9D
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Kras G12C In Complex With Compound 5C
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2022-08-10 Classification: ONCOPROTEIN/INHIBITOR Ligands: GDP, MG, IQC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: GDP, MG, IQC
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Kras G12C In Complex With Compound 7B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2022-08-10 Classification: ONCOPROTEIN/inhibitor Ligands: GDP, MG, SO4, IQN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-08-10
Ligands: GDP, MG, SO4, IQN
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Co-Complex Cyp46A1 With Compound 3F
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2022-07-27 Classification: OXIDOREDUCTASE Ligands: HEM, 0I1, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-27
Ligands: HEM, 0I1, EDO, GOL
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Molecular Mechanism Of The The Wake-Promoting Agent Tak-925
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2022-06-08 Classification: SIGNALING PROTEIN Ligands: A6F, OLA |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2022-06-08
Ligands: A6F, OLA
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Structure Of The Orexin-2 Receptor(Ox2R) Bound To Tak-925, Gi And Scfv16
Organism: Homo sapiens, Bos taurus, Synthetic construct
Method: ELECTRON MICROSCOPY Release Date: 2022-05-25 Classification: MEMBRANE PROTEIN Ligands: OLA, A6F |
Organism: Homo sapiens, Bos taurus, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2022-05-25
Ligands: OLA, A6F
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Co-Complex Cyp46A1 With 0420 (Compound 6)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2022-02-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, EDO, 04Y, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: HEM, EDO, 04Y, GOL
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Co-Complex Cyp46A1 With 0431 (Compound 17)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-02-23 Classification: HYDROLASE Ligands: HEM, 05D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: HEM, 05D
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Co-Complex Cyp46A1 With 7742 (Soticlestat/Tak-935))
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YBS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YBS
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Co-Complex Cyp46A1 With 8114 (3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCJ
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Co-Complex Cyp46A1 With 9129 (1B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCG
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Bacterial O-Glcnacase (Oga) With Compound
Organism: Escherichia coli k-12
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-01-13 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ACT, VUA, EDO |
Organism: Escherichia coli k-12
Method: X-RAY DIFFRACTION
Release Date: 2021-01-13
Ligands: ACT, VUA, EDO
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Crystal Structure Of Human Monoacylglycerol Lipase In Complex With Compound 3L
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2018-10-17 Classification: HYDROLASE/INHIBITOR Ligands: 9JX, PG4, EDO, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-10-17
Ligands: 9JX, PG4, EDO, CL