ISDA: 9ZWQ

Deposition Date 2026-01-03

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

9ZWQ

Keywords:

TRANSFERASE

Title:

Crystal structure of the N4BP2 polynucleotide kinase (PNK) domain in complex with ADP and Mg.

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.95 Å

R-Value Free:

0.22

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

I 2 2 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:NEDD4-binding protein 2
Gene (Uniprot):N4BP2
Chain IDs:A, B, C
Chain Length:0
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:Q86UW6 Pfam ID:PF13671 EC:3.-.-.-

Ligand Molecules

ADP

EDO

IPA

PO4

SO4

Primary Citation

Structure, Specificity, and Catalytic Mechanism of the Polynucleotide Kinase Domains from the Human N4BP2 Kinase Family

Wang, H, Stanley, R.E.Show

Nat Commun ? ? ? (2026)

Primary Citation of related structures

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