ISDA: 9ZRZ

Deposition Date 2025-12-21

Release Date 2026-06-03

Last Version Date 2026-06-03

Entry Detail

PDB ID:

9ZRZ

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

Cryo-EM structure of SHIV-elicited CI93-1365 Fab in complex with HIV Env trimer Q23-SCT27

Biological Source:

Source Organism(s):

Macaca mulatta (Taxon ID: 9544)
Human immunodeficiency virus (Taxon ID: 12721)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:CI93-1365 heavy chain
Chain IDs:A
Chain Length:247
Number of Molecules:1
Biological Source:Macaca mulatta

Protein Blast

Polymer Type:polypeptide(L)
Molecule:CI93-1365 light chain
Chain IDs:B
Chain Length:503
Number of Molecules:1
Biological Source:Macaca mulatta

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Envelope gp120
Gene (Uniprot):env
Chain IDs:C (auth: b), E (auth: d), G (auth: f)
Chain Length:503
Number of Molecules:3
Biological Source:Human immunodeficiency virus

UniProt ID:O55774

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Envelope gp41 ectodomain
Gene (Uniprot):env
Chain IDs:D (auth: c), F (auth: e), H (auth: g)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus

UniProt ID:O55774

Ligand Molecules

NAG

Primary Citation

Enhanced Priming Leads to Rapid Induction of Broadly Neutralizing HIV-1 Apex Antibodies

Roark, R.S, Shapiro, L, Kwong, P.D.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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