ISDA: 9ZRT

Deposition Date 2025-12-20

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9ZRT

Keywords:

PROTEIN TRANSPORT

Title:

Shigella flexneri type III secretion system (T3SS) protein IpaD bound to hemolysis blocking antibody fragment D13r-34

Biological Source:

Source Organism(s):

Shigella flexneri (Taxon ID: 623)
Macaca mulatta (Taxon ID: 9544)

Expression System(s):

Escherichia coli, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Invasin IpaD
Gene (Uniprot):ipaD
Chain IDs:A (auth: D)
Chain Length:357
Number of Molecules:1
Biological Source:Shigella flexneri

UniProt ID:P18013 Pfam ID:PF06511

Polymer Type:polypeptide(L)
Molecule:D13r-34 antibody fragment hea
Chain IDs:B (auth: H)
Chain Length:232
Number of Molecules:1
Biological Source:Macaca mulatta

Polymer Type:polypeptide(L)
Molecule:D13r-34 antibody fragment lig
Chain IDs:C (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Macaca mulatta

Ligand Molecules

Primary Citation

Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.

Gallant, R.M, Savarino, P, Pulido, S, Gilman, M.S.A, Lu, T, Hayes, J, Xerri, N.L, Williams, T, Ochoa, M.A, Dietz, Z, Peterson, E, Scott, T, Hartmann, F, Baker, S.G, Kaminski, R.W, Sok, D, Kruse, A.C, Picking, W, Capuano, S.V, Schmidt, H.R.Show

Sci Transl Med 18 eaef7084 eaef7084 (2026)

PMID: 42685149 DOI: 10.1126/scitranslmed.aef7084

Primary Citation of related structures

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