9ZRS image
Deposition Date 2025-12-20
Release Date 2026-09-16
Last Version Date 2026-09-16
Entry Detail
PDB ID:
9ZRS
Keywords:
PROTEIN TRANSPORT
Title:
Shigella flexneri type III secretion system (T3SS) protein IpaD bound to hemolysis blocking Fab D02-F2 and hemolysis enhancing Fab D02-E4
Biological Source:
Source Organism(s):
Shigella flexneri (Taxon ID: 623)
Macaca mulatta (Taxon ID: 9544)
Expression System(s):
Escherichia coli, Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.40 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZRS validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Invasin IpaD
Gene (Uniprot):ipaD
Chain IDs:A (auth: D)
Chain Length:357
Number of Molecules:1
Biological Source:Shigella flexneri
UniProt ID:P18013
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:D02-F2 antibody fragment heav
Chain IDs:B (auth: H)
Chain Length:222
Number of Molecules:1
Biological Source:Macaca mulatta
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:D02-F2 antibody fragment ligh
Chain IDs:C (auth: L)
Chain Length:219
Number of Molecules:1
Biological Source:Macaca mulatta
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:D02-E4 antibody fragment heav
Chain IDs:D (auth: O)
Chain Length:225
Number of Molecules:1
Biological Source:Macaca mulatta
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:D02-E4 antibody fragment ligh
Chain IDs:E (auth: P)
Chain Length:214
Number of Molecules:1
Biological Source:Macaca mulatta
Ligand Molecules
NA
Primary Citation
Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.
Sci Transl Med 18 eaef7084 eaef7084 (2026)
PMID: 42685149 DOI: 10.1126/scitranslmed.aef7084
Primary Citation of related structures
9ZRS
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