9ZRP image
Deposition Date 2025-12-20
Release Date 2026-07-29
Last Version Date 2026-07-29
Entry Detail
PDB ID:
9ZRP
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Neutralizing W049 antibody Fab fragment in complex with West Nile Virus EDIII
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
West Nile virus (Taxon ID: 11082)
Expression System(s):
Homo sapiens, Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.50 Å
R-Value Free:
0.26
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 21
9ZRP validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:W049 Fab Heavy Chain
Chain IDs:A, D (auth: H)
Chain Length:232
Number of Molecules:2
Biological Source:Homo sapiens
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:W049 Fab Light Chain
Chain IDs:B, E (auth: L)
Chain Length:215
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Envelope protein E
Gene (Uniprot):GP1
Chain IDs:C (auth: G), F (auth: S)
Chain Length:102
Number of Molecules:2
Biological Source:West Nile virus
UniProt ID:Q9Q6P4
Primary Citation
Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses.
Immunity 59 2015 2029.e9 (2026)
PMID: 42330958 DOI: 10.1016/j.immuni.2026.05.013
Primary Citation of related structures
9ZRP
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