ISDA: 9ZPL

Deposition Date 2025-12-16

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9ZPL

Keywords:

TRANSCRIPTION

Title:

Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in open clamp conformation

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.75 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPO21
Chain IDs:I (auth: A)
Chain Length:1733
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P04050 Pfam ID:PF04997, PF00623, PF04983, PF05000, PF04998, PF04992, PF04990, PF05001 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB2
Chain IDs:J (auth: B)
Chain Length:1224
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P08518 Pfam ID:PF04563, PF04561, PF04565, PF04566, PF04567, PF00562, PF04560 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB3
Chain IDs:A (auth: C)
Chain Length:318
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P16370 Pfam ID:PF01193, PF01000

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB4
Chain IDs:L (auth: D)
Chain Length:221
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20433 Pfam ID:PF03874

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB5
Chain IDs:B (auth: E)
Chain Length:215
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20434 Pfam ID:PF03871, PF01191

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPO26
Chain IDs:C (auth: F)
Chain Length:155
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20435 Pfam ID:PF01192

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB7
Chain IDs:D (auth: G)
Chain Length:171
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P34087 Pfam ID:PF03876, PF00575

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB8
Chain IDs:K (auth: H)
Chain Length:146
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20436 Pfam ID:PF03870

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB9
Chain IDs:E (auth: I)
Chain Length:122
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P27999 Pfam ID:PF02150, PF01096

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB10
Chain IDs:F (auth: J)
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P22139 Pfam ID:PF01194

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB11
Chain IDs:G (auth: K)
Chain Length:120
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38902 Pfam ID:PF13656

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPC10
Chain IDs:H (auth: L)
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P40422 Pfam ID:PF03604

Ligand Molecules

Primary Citation

Clamp conformational flexibility and dynamics in archaeal and eukaryotic RNA polymerases revealed by cryo-EM

Fordjour, G.N.R, Murakami, K, Armache, J.-P, Murakami, K.S.Show

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Primary Citation of related structures

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