ISDA: 9ZO5

Deposition Date 2025-12-15

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9ZO5

Keywords:

TRANSCRIPTION

Title:

Cryo-EM structure of the complete Pyrococcus furiosus RNA polymerase in open clamp conformation

Biological Source:

Source Organism(s):

Pyrococcus furiosus DSM 3638 (Taxon ID: 186497)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.05 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo1N
Chain IDs:A
Chain Length:907
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0M4 Pfam ID:PF04997, PF00623, PF04983, PF05000, PF04998 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):PF1564
Chain IDs:B
Chain Length:1117
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0M3 Pfam ID:PF04563, PF04561, PF04565, PF04566, PF04567, PF00562, PF04560 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo1C
Chain IDs:C
Chain Length:397
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0M5 Pfam ID:PF04998 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo3
Chain IDs:D
Chain Length:275
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0E4 Pfam ID:PF01193, PF01000 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo7
Chain IDs:E
Chain Length:189
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U439 Pfam ID:PF03876, PF00575 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo4
Chain IDs:F
Chain Length:120
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U216 Pfam ID:PF03874 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo5
Chain IDs:H
Chain Length:82
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0M2 Pfam ID:PF01191 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo6
Chain IDs:J (auth: K)
Chain Length:57
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U0E8 Pfam ID:PF01192 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo11
Chain IDs:G (auth: L)
Chain Length:95
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8U4N1 Pfam ID:PF13656 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo10
Chain IDs:I (auth: N)
Chain Length:65
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:P60292 Pfam ID:PF01194 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Gene (Uniprot):rpo12
Chain IDs:K (auth: P)
Chain Length:49
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638

UniProt ID:Q8TZI3 Pfam ID:PF03604 EC:2.7.7.6

Ligand Molecules

Primary Citation

Clamp conformational flexibility and dynamics in archaeal and eukaryotic RNA polymerases revealed by cryo-EM

Fordjour, G.N.R, Murakami, K, Armache, J.-P, Murakami, K.S.Show

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Primary Citation of related structures

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