ISDA: 9ZG6

Deposition Date 2025-12-02

Release Date 2026-10-28

Last Version Date 2026-11-04

Entry Detail

PDB ID:

9ZG6

Keywords:

RNA BINDING PROTEIN

Title:

Crystal structure of P. furiosus SRP54 NG domain T114A

Biological Source:

Source Organism(s):

Pyrococcus furiosus (Taxon ID: 2261)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.30 Å

R-Value Free:

0.21

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 2 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Signal recognition particle 5
Gene (Uniprot):srp54
Mutagens:T114A
Chain IDs:A
Chain Length:316
Number of Molecules:1
Biological Source:Pyrococcus furiosus

UniProt ID:Q8U070 EC:3.6.5.4

Ligand Molecules

GMP

GOL

SO4

Primary Citation

Structure and Function of Archaeal SRP54 Protein Mutants Associated with Human Severe Congenital Neutropenia.

Yang, M, Brim, A.D, Long, L.F, Wu, G.C, Schlichting, G.M, Denard, C.A, Bruner, S.D.Show

Acs Omega 11 63170 63178 (2026)

PMID: 42923585 DOI: 10.1021/acsomega.6c06315

Primary Citation of related structures

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