9ZDF image
Deposition Date 2025-11-25
Release Date 2026-11-04
Last Version Date 2026-11-04
Entry Detail
PDB ID:
9ZDF
Keywords:
PROTEIN BINDING/Immune System
Title:
factor VIIa-tissue factor-factor X-ixolaris complex in calcium ion-containing buffer
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Ixodes scapularis (Taxon ID: 6945)
Expression System(s):
Escherichia coli, Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.35 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZDF validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Factor VII Heavy Chain
Gene (Uniprot):F7
Chain IDs:A
Chain Length:254
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P08709 EC:3.4.21.21
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Factor VII light chain
Gene (Uniprot):F7
Chain IDs:B
Chain Length:152
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P08709 EC:3.4.21.21
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tissue factor
Gene (Uniprot):F3
Chain IDs:C
Chain Length:219
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P13726
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Factor X heavy chain
Gene (Uniprot):F10
Chain IDs:D
Chain Length:306
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P00742 EC:3.4.21.6
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Factor X light chain
Gene (Uniprot):F10
Chain IDs:E
Chain Length:139
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P00742 EC:3.4.21.6
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ixolaris
Chain IDs:F
Chain Length:140
Number of Molecules:1
Biological Source:Ixodes scapularis
UniProt ID:Q964Q0
Ligand Molecules
NA
Primary Citation
Structure of the extrinsic factor Xase substrate complex with the bi-Kunitz inhibitor ixolaris.
Blood Adv ? ? ? (2026)
PMID: 42913430 DOI: 10.1182/bloodadvances.2026020317
Primary Citation of related structures
9ZDF
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