9ZCX image
Deposition Date 2025-11-24
Release Date 2026-11-04
Last Version Date 2026-11-04
Entry Detail
PDB ID:
9ZCX
Keywords:
PROTEIN BINDING
Title:
factor VIIa-tissue factor-factor X-ixolaris complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Ixodes scapularis (Taxon ID: 6945)
Expression System(s):
Escherichia coli, Spodoptera aff. frugiperda 1 bold-2017
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
5.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZCX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Coagulation factor VII Heavy
Gene (Uniprot):F7
Chain IDs:A
Chain Length:254
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P08709 EC:3.4.21.21
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Factor VII light chain
Gene (Uniprot):F7
Chain IDs:B
Chain Length:152
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P08709 EC:3.4.21.21
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tissue factor
Gene (Uniprot):F3
Chain IDs:C
Chain Length:205
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P13726
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Coagulation factor X
Gene (Uniprot):F10
Chain IDs:D
Chain Length:306
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P00742 EC:3.4.21.6
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ixolaris
Chain IDs:E (auth: F)
Chain Length:140
Number of Molecules:1
Biological Source:Ixodes scapularis
UniProt ID:Q964Q0
Ligand Molecules
NA
Primary Citation
Structure of the extrinsic factor Xase substrate complex with the bi-Kunitz inhibitor ixolaris.
Blood Adv ? ? ? (2026)
PMID: 42913430 DOI: 10.1182/bloodadvances.2026020317
Primary Citation of related structures
9ZCX
Feedback Form
Name
Email
Institute
Feedback