ISDA: 9ZCL

Deposition Date 2025-11-23

Release Date 2026-06-17

Last Version Date 2026-06-17

Entry Detail

PDB ID:

9ZCL

Keywords:

IMMUNE SYSTEM

Title:

N17.3.2 NRASQ61K HLA A1 complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.30 Å

R-Value Free:

0.25

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 43 21 2

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:N17.3.2 TCR alpha
Chain IDs:D (auth: A)
Chain Length:212
Number of Molecules:1
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:N17.3.2 TCR beta
Chain IDs:E (auth: B)
Chain Length:241
Number of Molecules:1
Biological Source:Homo sapiens

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:HLA class I histocompatibilit
Chain IDs:B (auth: C)
Chain Length:276
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q59GJ2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:C (auth: D)
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P61769 Pfam ID:PF07654

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:ILE-LEU-ASP-THR-ALA-GLY-LYS-G
Gene (Uniprot):KRAS
Chain IDs:A (auth: P)
Chain Length:10
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01116 EC:3.6.5.2

Ligand Molecules

SO4

Primary Citation

Structural basis for oligoclonal T cell recognition of a shared NRAS cancer neoantigen

Sharma, V.K, Gallagher, D.T, Mariuzza, R.A.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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