9YW4 image
Deposition Date 2025-10-23
Release Date 2026-06-17
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9YW4
Keywords:
IMMUNE SYSTEM
Title:
T cell receptor N17.2 complexed w/ HLA.A1 and NRAS peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.10 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 43 21 2
9YW4 validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:TCR Alpha chain
Chain IDs:A
Chain Length:206
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:TCR Beta chain
Chain IDs:B
Chain Length:244
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:HLA class I histocompatibilit
Chain IDs:D
Chain Length:276
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Chain IDs:E
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:NRAS neopeptide with oncogeni
Chain IDs:C (auth: P)
Chain Length:10
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NA
Primary Citation
Structural basis for oligoclonal T cell recognition of a shared NRAS cancer neoantigen.
Structure ? ? ? (2026)
PMID: 42476141 DOI: 10.1016/j.str.2026.06.008
Primary Citation of related structures
9YW4
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