9ZCJ image
Deposition Date 2025-11-23
Release Date 2026-09-30
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9ZCJ
Keywords:
Title:
Therapeutic antibody with captured antigen
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.60 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Serine protease complement C2
Gene (Uniprot):C2
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Fab light chain
Chain IDs:C, E (auth: G)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Fab heavy chain
Chain IDs:D, F (auth: I)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
Primary Citation
CSL305: A Dual Functional Therapeutic Antibody Targeting Complement C2 and FcRn.
Int J Mol Sci 27 ? ? (2026)
PMID: 41828601 DOI: 10.3390/ijms27052383
Primary Citation of related structures
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