9ZB9 image
Deposition Date 2025-11-20
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
9ZB9
Keywords:
TRANSFERASE/INHIBITOR
Title:
Cryo-EM Structure of Human GGPPS Bound to Selective Inhibitor CML-07-119
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
1.95 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ZB9 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Geranylgeranyl pyrophosphate
Gene (Uniprot):GGPS1
Chain IDs:A, B, C, D (auth: F), E (auth: G), F (auth: H)
Chain Length:301
Number of Molecules:6
Biological Source:Homo sapiens
UniProt ID:O95749 Pfam ID:PF00348 EC:2.5.1.29
Ligand Molecules
A1C1E
MG
Primary Citation
Cryo-EM Structure of Human GGPPS Bound to Selective Inhibitor CML-07-119
To Be Published ? ? ? (?)
Primary Citation of related structures
9ZB8
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