9Z9L image
Deposition Date 2025-11-18
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9Z9L
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Human immunodeficiency virus 1 (Taxon ID: 11676)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.49 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9Z9L validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Q23.MD39 Surface protein gp12
Gene (Uniprot):env
Chain IDs:G (auth: A), K (auth: C), L (auth: G)
Chain Length:467
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:O55774
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Q23.MD39 Transmembrane protei
Gene (Uniprot):env
Chain IDs:H (auth: B), I (auth: D), J (auth: I)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:O55774
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody 35O22 Fab heavy chai
Chain IDs:A (auth: E), C (auth: H)
Chain Length:243
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:9Z9L
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody 35O22 Fab light chai
Chain IDs:B (auth: F), F (auth: L)
Chain Length:216
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:9Z9L
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody CH01 variable domain
Chain IDs:D (auth: J)
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9Z9L
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody CH01 variable domain
Chain IDs:E (auth: K)
Chain Length:133
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9Z9L
Ligand Molecules
NAG
Primary Citation
Deep Mining of the Human Antibody Repertoire Identifies Frequent and Genetically Diverse CDRH3 Topologies Targetable by Vaccination
Proc. Natl. Acad. Sci. U.S.A. ? ? ? (2026)
DOI: 10.1073/pnas.2532810123
Primary Citation of related structures
9DHW
9DIM
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