ISDA: 9Z5R

Deposition Date 2025-11-12

Release Date 2026-11-04

Last Version Date 2026-11-04

Entry Detail

PDB ID:

9Z5R

Keywords:

HYDROLASE

Title:

Cryo-EM of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in presence of calcium and compound UM-52 (unbound)

Biological Source:

Source Organism(s):

Oryctolagus cuniculus (Taxon ID: 9986)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sarcoplasmic/endoplasmic reti
Gene (Uniprot):ATP2A1
Chain IDs:A
Chain Length:994
Number of Molecules:1
Biological Source:Oryctolagus cuniculus

UniProt ID:P04191 EC:7.2.2.10

Ligand Molecules

Primary Citation

Cryo-EM reveals a transmembrane allosteric site and activation mechanism for the SERCA calcium pump

Nguyen, V.H, Primeau, J.O, Cruz-Cortes, C, Lemieux, M.J, Espinoza-Fonseca, M, Young, H.S.Show

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Primary Citation of related structures

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