9Z3L image
Deposition Date 2025-11-07
Release Date 2026-11-11
Last Version Date 2026-11-11
Entry Detail
PDB ID:
9Z3L
Keywords:
TRANSFERASE
Title:
Complex of phosphorylated p38-alpha and MK2 with a molecular glue
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.70 Å
R-Value Free:
0.26
R-Value Work:
0.22
Space Group:
P 1 21 1
9Z3L validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Mitogen-activated protein kin
Gene (Uniprot):MAPK14
Chain IDs:A, B, C, D
Chain Length:363
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:Q16539 EC:2.7.11.24
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:MAP kinase-activated protein
Gene (Uniprot):MAPKAPK2
Chain IDs:E, F, G, H
Chain Length:363
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P49137 EC:2.7.11.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR A, B, C, D TYR modified residue
TPO A, B, C, D THR modified residue
Ligand Molecules
A1CZ8
EDO
GOL
MLI
Primary Citation
Diverse Computational Strategies Enable the Discovery of p38-alpha-MK2 Molecular Glues
To Be Published ? ? ? (?)
Primary Citation of related structures
9Z3L
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