ISDA: 9YVW

Deposition Date 2025-10-23

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

9YVW

Keywords:

Viral protein/DNA

Title:

HIV-1 RT F227C with DNA and islatravir-triphosphate

Biological Source:

Source Organism(s):

Human immunodeficiency virus 1 (Taxon ID: 11676)

Expression System(s):

Escherichia coli bl21, Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:P66
Gene (Uniprot):pol
Mutagens:F227C
Chain IDs:A
Chain Length:560
Number of Molecules:1
Biological Source:Human immunodeficiency virus 1

UniProt ID:A7YKL0

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:P51
Gene (Uniprot):pol
Chain IDs:B
Chain Length:452
Number of Molecules:1
Biological Source:Human immunodeficiency virus 1

UniProt ID:A7YKL0

Polymer Type:polydeoxyribonucleotide
Molecule:Primer
Chain IDs:C (auth: P)
Chain Length:21
Number of Molecules:1
Biological Source:Human immunodeficiency virus 1

Polymer Type:polydeoxyribonucleotide
Molecule:Template
Chain IDs:D (auth: T)
Chain Length:27
Number of Molecules:1
Biological Source:Human immunodeficiency virus 1

Ligand Molecules