ISDA: 9YEO

Deposition Date 2025-09-24

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9YEO

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of double-bound FDG antibody VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer

Biological Source:

Source Organism(s):

Human immunodeficiency virus 1 (Taxon ID: 11676)
Human immunodeficiency virus (Taxon ID: 12721)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.64 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP.664 gp41
Gene (Uniprot):env
Chain IDs:A, G (auth: B), M (auth: I)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1

UniProt ID:Q2N0S5

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP.664 gp120
Gene (Uniprot):env
Chain IDs:B (auth: C), H (auth: D), N (auth: J)
Chain Length:481
Number of Molecules:3
Biological Source:Human immunodeficiency virus

UniProt ID:Q2N0S6

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:VRC49.01 heavy
Chain IDs:C (auth: K), E (auth: M), I (auth: E), K (auth: G)
Chain Length:125
Number of Molecules:4
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:VRC19.01 light
Chain IDs:D (auth: L), F (auth: N), J (auth: F), L (auth: H)
Chain Length:107
Number of Molecules:4
Biological Source:Homo sapiens

Ligand Molecules

NAG

Primary Citation

Cryo-EM structure of VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer

Gorman, J, Kwong, P.D.Show

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