ISDA: 9YCY

Deposition Date 2025-09-19

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

9YCY

Keywords:

MEMBRANE PROTEIN

Title:

Neurotensin Receptor 1 (NTSR1) bound to Octotensin in complex with Gi3 in the Canonical Orientation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Octopus vulgaris (Taxon ID: 6645)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Spodoptera frugiperda, Synthetic construct, Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI3
Chain IDs:E (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P08754 Pfam ID:PF00503

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:A (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:B (auth: C)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tachykinin-1
Chain IDs:C (auth: L)
Chain Length:0
Number of Molecules:1
Biological Source:Octopus vulgaris

UniProt ID:Q8I6S3

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Neurotensin receptor type 1
Gene (Uniprot):NTSR1
Chain IDs:D (auth: R)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P30989 Pfam ID:PF00001

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:F (auth: S)
Chain Length:0
Number of Molecules:1
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Prey-specific toxins provide broad venom activity in cephalopods

Koch, L.T, Yeung, H.Y, Torres, J.P, Brandt, Z, Palomino, S, Ramiro, I.B.L, Acyatan, Z, Schumann, N, Vo, A.A, Chase, K, Engholm, E, Jensen, K.J, Hansen, L.H, Peterson, R.T, Robertson, M.J, Ptwardhan, A, Schjoldager, K.T, Safavi-Hemami, H.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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