9YAQ image
Deposition Date 2025-09-16
Release Date 2026-07-22
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9YAQ
Keywords:
Title:
The structure of the cardiac native cross bridge in the rigor state, myosin heads bound to actin molecules 5 and 6.
Biological Source:
Source Organism(s):
Sus scrofa (Taxon ID: 9823)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
4.63 Å
Aggregation State:
FILAMENT
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Actin, alpha cardiac muscle 1
Gene (Uniprot):ACTC1
Chain IDs:A, B, C, D
Chain Length:0
Number of Molecules:4
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Tropomyosin alpha-1 chain
Gene (Uniprot):TPM1
Chain IDs:E, F, G, H
Chain Length:0
Number of Molecules:4
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Troponin T2, cardiac type
Gene (Uniprot):TNNT2
Chain IDs:I, P
Chain Length:0
Number of Molecules:2
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Myosin-7
Gene (Uniprot):MYH7
Chain IDs:J, K
Chain Length:0
Number of Molecules:2
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Myosin light chain 3
Gene (Uniprot):MYL3
Chain IDs:L, M
Chain Length:0
Number of Molecules:2
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Troponin C, slow skeletal and
Gene (Uniprot):TNNC1
Chain IDs:N
Chain Length:0
Number of Molecules:1
Biological Source:Sus scrofa
Polymer Type:polypeptide(L)
Molecule:Troponin I, cardiac muscle
Gene (Uniprot):TNNI3
Chain IDs:O
Chain Length:0
Number of Molecules:1
Biological Source:Sus scrofa
Primary Citation
The structure of the native cardiac crossbridge in the rigor state.
Sci Adv 12 eaeg1209 eaeg1209 (2026)
PMID: 42647613 DOI: 10.1126/sciadv.aeg1209
Primary Citation of related structures
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