ISDA: 9XJZ

Deposition Date 2025-11-05

Release Date 2026-11-11

Last Version Date 2026-11-11

Entry Detail

PDB ID:

9XJZ

Keywords:

TRANSCRIPTION

Title:

Crystal Structure of Nur77 LBD in complex with HTPA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.08 Å

R-Value Free:

0.22

R-Value Work:

0.17

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear receptor subfamily 4i
Gene (Uniprot):NR4A1
Chain IDs:A, B
Chain Length:248
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P22736

Ligand Molecules

A1E0K

GOL

Primary Citation

Copper ion-induced MYH9 polymerization executes cuproptosis.

Wu, L.Z, Mi, X.Y, Liu, Z.J, Ding, Y, Hong, W.B, Cai, C.X, Hu, H.J, Ai, Y.L, Zhao, B.X, Qiu, D.D, Ma, J.S, Chen, X.Q, You, H, Lin, T, Li, F.N, Hong, X.H, Chen, H.Z, Wu, Q.Show

Cell 189 6951 6967.e12 (2026)

PMID: 42735689 DOI: 10.1016/j.cell.2026.08.030

Primary Citation of related structures

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