ISDA: 9XEP

Deposition Date 2025-10-28

Release Date 2026-11-04

Last Version Date 2026-11-04

Entry Detail

PDB ID:

9XEP

Keywords:

PROTEIN FIBRIL

Title:

Type Ic alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.83 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Alpha-synuclein
Gene (Uniprot):SNCA
Chain IDs:A, B, C, D, E, F
Chain Length:140
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:P37840

Ligand Molecules

Primary Citation

Rapid Parkinson's Disease Diagnosis Using One-Spin RT-QuIC on Plasma Extracellular Vesicles: A Pilot Study

Yan, Y, Hu, C, Jin, Y, Liu, Y, Liu, T, Zheng, R, Chen, Y, Liu, Y, Yan, Y, Zhang, B, Shi, Y, Pu, J, Zhong, Z.Show

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Primary Citation of related structures

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